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Plasma renin measurements are unrelated to mineralocorticoid replacement dose in patients with primary adrenal insufficiency

Abstract:

CONTEXT:No consensus exists for optimization of mineralocorticoid therapy in patients with primary adrenal insufficiency. OBJECTIVE:To explore the relationship between mineralocorticoid (MC) replacement dose, plasma renin concentration (PRC), and clinically important variables to determine which are most helpful in guiding MC dose titration in primary adrenal insufficiency. DESIGN:Observational, retrospective, longitudinal analysis. PATIENTS:A total of 280 patients (with 984 clinical visits a...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1210/clinem/dgz055

Authors


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Role:
Author
ORCID:
0000-0001-7808-5735
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Name:
Medical Research Council
Grant:
MR/P011462/1
Publisher:
Oxford University Press
Journal:
Journal of clinical endocrinology and metabolism More from this journal
Volume:
105
Issue:
1
Publication date:
2019-10-16
Acceptance date:
2019-09-20
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
Pmid:
31613957
Language:
English
Pubs id:
1068190
Local pid:
pubs:1068190
Deposit date:
2020-02-06

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