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Drosophila learn opposing components of a compound food stimulus

Abstract:

Dopaminergic neurons provide value signals in mammals and insects. During Drosophila olfactory learning, distinct subsets of dopaminergic neurons appear to assign either positive or negative value to odor representations in mushroom body neurons. However, it is not known how flies evaluate substances that have mixed valence. Here we show that flies form short-lived aversive olfactory memories when trained with odors and sugars that are contaminated with the common insect repellent DEE...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
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Publisher copy:
10.1016/j.cub.2014.05.078

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Klappenbach, M More by this author
Vrontou, E More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Publisher:
Elsevier (Cell Press) Publisher's website
Journal:
Current Biology Journal website
Volume:
24
Issue:
15
Pages:
1723-1730
Publication date:
2014-07-17
Acceptance date:
2014-05-21
DOI:
EISSN:
1879-0445
ISSN:
0960-9822
URN:
uuid:fae451c8-0c15-4680-91ad-312a52844845
Source identifiers:
480227
Local pid:
pubs:480227
Keywords:

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