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Radiation damage to nucleoprotein complexes in macromolecular crystallography

Abstract:

Significant progress has been made in macromolecular crystallography over recent years in both the understanding and mitigation of X-ray induced radiation damage when collecting diffraction data from crystalline proteins. In contrast, despite the large field that is productively engaged in the study of radiation chemistry of nucleic acids, particularly of DNA, there are currently very few X-ray crystallographic studies on radiation damage mechanisms in nucleic acids. Quantitative comparison o...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
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Name:
Biotechnology and Biological Sciences Research Council
Grant:
BB/E000878/1/
More from this funder
Name:
Engineering and Physical Sciences Research Council
Grant:
EP/E500595/1
1363961
Publisher:
International Union of Crystallography
Journal:
Journal of synchrotron radiation More from this journal
Volume:
22
Issue:
2
Pages:
213-224
Publication date:
2015-03-01
Acceptance date:
2014-11-30
DOI:
EISSN:
1600-5775
ISSN:
0909-0495
Pmid:
25723923
Language:
English
Keywords:
Pubs id:
pubs:509922
UUID:
uuid:fae1103a-4ba5-4674-99a0-af67a683a1b6
Local pid:
pubs:509922
Source identifiers:
509922
Deposit date:
2017-02-03

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