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Foregut mesenchyme contributes cells to islets during pancreatic development in a 3-dimensional avian model

Abstract:

Current interest in the potential use of pancreatic stem-cells in the treatment of insulin dependent diabetes mellitus has led to increased research into normal pancreatic development. Pancreatic organogenesis involves branching morphogenesis of undifferentiated epithelium within surrounding mesenchyme. Current understanding is that the pancreatic islets develop exclusively from the epithelium of the embryonic buds. However, a cellular contribution to islets by mesenchyme has not been conclus...

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Publisher copy:
10.4161/org.1.2.1254

Authors


Jayanthi, NVG More by this author
Teague, WJ More by this author
Johnson, PRV More by this author
Journal:
Organogenesis
Volume:
1
Issue:
2
Pages:
45-51
Publication date:
2005-10-05
DOI:
ISSN:
1547-6278
URN:
uuid:faa696b9-0067-484a-890d-065d33125259
Source identifiers:
244913
Local pid:
pubs:244913

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