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Journal article

Halofantrine pharmacokinetics in Kenyan children with non-severe and severe malaria.

Abstract:

1. Kenyan children with uncomplicated malaria given oral halofantrine (HF; non-micronised suspension; 8 mg base kg-1 body weight 6 hourly for three doses) showed wide variation in the disposition of HF and desbutylhalofantrine (HFm). 2. Eight Kenyan children with severe (prostrate) falciparum malaria who were receiving intravenous quinine, were given the same HF regimen by nasogastric tube. One patient had undetectable HF and two had undetectable HFm at all times after drug administration. 3....

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Publication status:
Published

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Journal:
British journal of clinical pharmacology More from this journal
Volume:
39
Issue:
3
Pages:
283-287
Publication date:
1995-03-01
DOI:
EISSN:
1365-2125
ISSN:
0306-5251
Language:
English
Keywords:
Pubs id:
pubs:44704
UUID:
uuid:fa89aaa5-0a16-4c6c-9637-6fe3eabd314b
Local pid:
pubs:44704
Source identifiers:
44704
Deposit date:
2012-12-19

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