Journal article
Nerve growth factor receptor mRNA distribution in human brain: normal levels in basal forebrain in Alzheimer's disease.
- Abstract:
-
Nerve growth factor (NGF) receptor mRNA was found to be widely distributed throughout the human central nervous system, with the highest levels in the basal forebrain; this suggests that NGF may function as a retrograde trophic messenger for basal forebrain magnocellular cholinergic nerve cells. The degeneration of the latter constitutes one of the main features of Alzheimer's disease and it may be responsible for some of the cognitive impairment that characterizes the disease. No evidence wa...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/0169-328x(89)90011-9
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Authors
Bibliographic Details
- Journal:
- Brain research. Molecular brain research
- Volume:
- 5
- Issue:
- 1
- Pages:
- 1-7
- Publication date:
- 1989-01-01
- DOI:
- ISSN:
-
0169-328X
- Source identifiers:
-
35186
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:35186
- UUID:
-
uuid:fa80fd27-c565-4975-b66f-7ed00c6bfd7f
- Local pid:
- pubs:35186
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1989
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