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Hepatocyte growth factor in normal and diseased bone and joint tissues.

Abstract:

Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which, like its receptor c-Met, is widely expressed in osteoarticular tissues. HGF has profound effects on cell motility and differentiation and tissue morphogenesis and angiogenesis. HGF plays an important role in normal bone and cartilage turnover. Changes in HGF/c-Met have also been linked to pathophysiological changes in several bone and joint disorders. HGF has been implicated in the pathogenesis of inflammatory changes in...

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Publisher copy:
10.2174/157339706775697017

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Current rheumatology reviews More from this journal
Volume:
2
Issue:
1
Pages:
1-7
Publication date:
2006-02-01
DOI:
EISSN:
1875-6360
ISSN:
1573-3971
Language:
English
Keywords:
Pubs id:
pubs:108206
UUID:
uuid:fa76d678-6fb1-4c65-b8bf-d2a5ba512463
Local pid:
pubs:108206
Source identifiers:
108206
Deposit date:
2012-12-19

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