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PedVacc 002: A phase I/II randomized clinical trial of MVA.HIVA vaccine administered to infants born to human immunodeficiency virus type 1-positive mothers in Nairobi

Abstract:

A safe, effective vaccine for breastfeeding infants born to HIV-1-positive mothers could complement antiretroviral therapy (ART) for prevention of mother-to-child transmission of HIV-1. To date, only a few HIV-1 vaccine candidates have been tested in infants. Trial design: A phase I/II randomized controlled trial PedVacc 002 was conducted to determine the safety and immunogenicity of a single, low dose of MVA.HIVA vaccine delivered intramuscularly to healthy 20-week-old infants born to HIV-1-...

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Publisher:
Elsevier
Journal:
Vaccine More from this journal
Volume:
32
Issue:
44
Pages:
5801-5808
Publication date:
2014-10-07
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Language:
English
Keywords:
Pubs id:
pubs:489204
UUID:
uuid:fa2d1546-ad46-4147-9cd6-7fd74b6d8133
Local pid:
pubs:489204
Source identifiers:
489204
Deposit date:
2014-11-14

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