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Journal article

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Abstract:

Atrial fibrillation affects more than 33 million people worldwide and increases the risk of stroke, heart failure, and death. Fourteen genetic loci have been associated with atrial fibrillation in European and Asian ancestry groups. To further define the genetic basis of atrial fibrillation, we performed large-scale, trans-ancestry meta-analyses of common and rare variant association studies. The genome-wide association studies (GWAS) included 17,931 individuals with atrial fibrillation and 1...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1038/ng.3843

Authors


Christophersen, IE More by this author
Rienstra, M More by this author
Roselli, C More by this author
Geelhoed, B More by this author
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Publisher:
Springer Nature Publisher's website
Journal:
Nature Genetics Journal website
Volume:
49
Issue:
6
Pages:
946-952
Publication date:
2017-06-05
Acceptance date:
2017-03-20
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
Pubs id:
pubs:695516
URN:
uri:f9f95006-10fd-44af-bbb8-1d85b6189c2b
UUID:
uuid:f9f95006-10fd-44af-bbb8-1d85b6189c2b
Local pid:
pubs:695516
Language:
English

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