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Identification of anti-retinal antibodies in patients with age-related macular degeneration.

Abstract:

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in industrial counties. Recent findings indicate that the autoimmunity is involved in the pathogenesis of the disease. However, there is no autoantibody biomarker applied in a clinical setting for diagnosis and prognosis of AMD. In order to reveal retinal antigens targeted by serum IgG from AMD patients, mouse retinal tissue proteins were separated by 2-dimensional electrophoresis and the proteins in the imm...

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Publisher copy:
10.1016/j.yexmp.2012.03.007

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Experimental and molecular pathology More from this journal
Volume:
93
Issue:
2
Pages:
193-199
Publication date:
2012-10-01
DOI:
EISSN:
1096-0945
ISSN:
0014-4800
Language:
English
Keywords:
Pubs id:
pubs:340335
UUID:
uuid:f9f73485-fab0-479d-8ceb-6f41b85dfe59
Local pid:
pubs:340335
Source identifiers:
340335
Deposit date:
2012-12-19

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