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Validation of microarray comparative genomic hybridization for comprehensive chromosome analysis of embryos.

Abstract:

OBJECTIVE: To validate and determine the best array-comparative genomic hybridization (aCGH; array-CGH) protocols for preimplantation genetic screening (PGS). DESIGN: Embryos had one cell removed as a biopsy specimen and analyzed by one of two array-CGH protocols. Abnormal embryos were reanalyzed by fluorescence in situ hybridization (FISH). SETTING: Reference laboratory. PATIENT(S): Patients donating embryos or undergoing PGS. INTERVENTION(S): Embryo biopsy, array-CGH, FISH reanalysis. MAIN...

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Publication status:
Published

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Journal:
Fertility and sterility More from this journal
Volume:
95
Issue:
3
Pages:
953-958
Publication date:
2011-03-01
DOI:
EISSN:
1556-5653
ISSN:
0015-0282
Language:
English
Keywords:
Pubs id:
pubs:248538
UUID:
uuid:f9bbe2ca-9b29-4351-b145-fd5b3e5a9253
Local pid:
pubs:248538
Source identifiers:
248538
Deposit date:
2013-11-16

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