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Meaning in life and vagally-mediated heart rate variability: evidence of a quadratic relationship at baseline and vagal reactivity differences

Abstract:
Higher meaning in life (MIL) consistently predicts better health, but the physiological processes underlying this relationship are not well understood. This study examined the relationship between MIL and vagally-mediated heart rate variability (VmHRV) under resting (N = 77), stressor (n = 73), and mindfulness intervention (n = 72) conditions. Regression was used for MIL-VmHRV analyses at baseline, and longitudinal mixed models were used to examine phasic changes in VmHRV as a function of MIL. Regression revealed a quadratic MIL-VmHRV relationship, and mixed models linked higher MIL to greater stress-reactivity but not enhanced stress-attenuation. MIL and mindfulness did not interact to influence VmHRV recovery after experimental stress. Findings suggest that cardiac vagal tone and cardiac vagal reactivity are linked to MIL, shedding light on the physiology underlying MIL and its health associations.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ijpsycho.2021.03.001

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
ORCID:
0000-0002-2069-2177


Publisher:
Elsevier
Journal:
International Journal of Psychophysiology More from this journal
Volume:
165
Pages:
101-111
Place of publication:
Netherlands
Publication date:
2021-03-18
Acceptance date:
2021-03-04
DOI:
EISSN:
1872-7697
ISSN:
0167-8760
Pmid:
33745963


Language:
English
Pubs id:
1335778
Local pid:
pubs:1335778
Deposit date:
2026-03-05
ARK identifier:

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