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A clinico-radiological phenotype of voltage-gated potassium channel complex antibody-mediated disorder presenting with seizures and basal ganglia changes.

Abstract:

In childhood, central nervous system (CNS) presentations associated with antibodies to voltage-gated potassium channel (VGKC) complex include limbic encephalitis, status epilepticus, epileptic encephalopathy, and autistic regression. We report the cases of two individuals (a 6-year-old male and an 11-year-old female) who presented with an acute-onset explosive seizure disorder with positive VGKC complex antibodies and bilateral basal ganglia changes on magnetic resonance imaging (MRI). Both p...

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Publication status:
Published

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Authors


Hacohen, Y More by this author
Siddiqui, A More by this author
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Journal:
Developmental medicine and child neurology
Volume:
54
Issue:
12
Pages:
1157-1159
Publication date:
2012-12-05
DOI:
EISSN:
1469-8749
ISSN:
0012-1622
URN:
uuid:f933d4c4-e571-4d76-b49d-8c071f13668e
Source identifiers:
344287
Local pid:
pubs:344287

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