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Modelling the first dose of measles vaccination: the role of maternal immunity, demographic factors, and delivery systems.

Abstract:

Measles vaccine efficacy is higher at 12 months than 9 months because of maternal immunity, but delaying vaccination exposes the children most vulnerable to measles mortality to infection. We explored how this trade-off changes as a function of regionally varying epidemiological drivers, e.g. demography, transmission seasonality, and vaccination coverage. High birth rates and low coverage both favour early vaccination, and initiating vaccination at 9-11 months, then switching to 12-14 months ...

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Publication status:
Published

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Publisher copy:
10.1017/s0950268810001329

Authors


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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Ferrari, M More by this author
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Journal:
Epidemiology and infection
Volume:
139
Issue:
2
Pages:
265-274
Publication date:
2011-02-05
DOI:
EISSN:
1469-4409
ISSN:
0950-2688
URN:
uuid:f91651b1-66e1-430d-961f-55d8471b1f12
Source identifiers:
314533
Local pid:
pubs:314533

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