CD4(+) regulatory T cells.

Journal article

There is now compelling evidence that CD4(+) T cells that specialize in the suppression of immune responses play a key role in the control of immune pathology. Recently, there have been a number of reports that have provided information on the generation of CD4(+) regulatory T cells in the thymus and in the periphery. These cells have also been identified in humans, paving the way for analysis of the function of CD4(+) regulatory T cells in immune-mediated disease.

Authors: Read, S; Powrie, F

• Publication status: Published
• Journal: Current opinion in immunology
• Volume: 13
• Issue: 6
• Pages: 644-649
• Publication date: 2001-12-01
• DOI: 10.1016/s0952-7915(01)00273-4
• EISSN: 1879-0372
• ISSN: 0952-7915
• Language: English
• Keywords: Humans; T-Lymphocytes, Regulatory; Cell Adhesion; Mice; Lymphocyte Activation; Animals; Receptors, Interleukin-2; Cytokines; Thymus Gland; T-Lymphocyte Subsets