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Journal article

3' non-coding region sequences in eukaryotic messenger RNA.

Abstract:
The sequence A-A-U-A-A-A is present in six different purified messenger RNA molecules (specifically the alpha-and beta-globulin mRNAs of rabbit and human, the immunoglobulin light chain mRNA of mouse (MOPC 21) and the ovalbumin mRNA of chicken) about 20 residues away from the 3'-terminal poly (A) sequence. In addition, a large selection of the 3' non-coding regions of rabbit and human globulin mRNAs (both the alpha and beta globin mRNAs) are 85% homologous, demonstrating that this region is significantly conserved in evolution.
Publication status:
Published

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Publisher copy:
10.1038/263211a0

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Brownlee, GG More by this author
Journal:
Nature
Volume:
263
Issue:
5574
Pages:
211-214
Publication date:
1976-09-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:f8f7971e-5efc-4c48-8cd6-e555ebf531e2
Source identifiers:
23080
Local pid:
pubs:23080

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