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Partition-associated incompatibility caused by random assortment of pure plasmid clusters.

Abstract:

Summary Bacterial plasmids and chromosomes encode centromere-like partition loci that actively segregate DNA before cell division. The molecular mechanism behind DNA segregation in bacteria is largely unknown. Here we analyse the mechanism of partition-associated incompatibility for plasmid pB171, a phenotype associated with all known plasmid-encoded centromere loci. An R1 plasmid carrying par2 from plasmid pB171 was destabilized by the presence of an F plasmid carrying parC1, parC2 or the en...

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Publication status:
Published

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Authors


Ebersbach, G More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Journal:
Molecular microbiology
Volume:
56
Issue:
6
Pages:
1430-1440
Publication date:
2005-06-05
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
URN:
uuid:f8ecf0b9-44c7-458c-818e-73d65754ad08
Source identifiers:
100274
Local pid:
pubs:100274

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