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Pharmacogenomics of statin therapy: any new insights in efficacy or safety?

Abstract:

PURPOSE OF REVIEW: To examine the current evidence concerning the effects of genetic variation on statin-related low-density lipoprotein cholesterol reductions, clinical efficacy, and adverse events and the relevance for patient care. RECENT FINDINGS: Recent years have seen the emergence of large-scale genetic experiments, including genome-wide association studies and candidate gene studies, exploring the impact of common genetic variation on patient response to statins. These studies have bu...

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Publication status:
Published

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Authors


Hopewell, JC More by this author
Armitage, J More by this author
Publisher:
Lippincott Williams and Wilkins
Journal:
Current opinion in lipidology
Volume:
25
Issue:
6
Pages:
438-445
Publication date:
2014-12-05
DOI:
EISSN:
1473-6535
ISSN:
0957-9672
URN:
uuid:f88c531c-815c-4167-aed8-44a6cac1cdf7
Source identifiers:
487210
Local pid:
pubs:487210
Language:
English
Keywords:

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