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Journal article

In vitro immune modulation by antibodies coupled to tumour cells.

Abstract:

Modification of autologous tumour cells to express the immune costimulator B7.1 is a potential strategy for immunotherapy of cancer. Previously, this has involved introduction of genetic material into cells, in vitro culture, and confirmation of the protein product on the cell surface. This is possible only if sufficient tumour is obtainable and efficiently modified in a short time. Whilst progress has been made on ex vivo tumour cell culture and transfection/infection procedures there are st...

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Publication status:
Published

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Publisher copy:
10.1038/sj.gt.3300534

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Journal:
Gene therapy More from this journal
Volume:
4
Issue:
12
Pages:
1350-1360
Publication date:
1997-12-01
DOI:
EISSN:
1476-5462
ISSN:
0969-7128
Language:
English
Keywords:
Pubs id:
pubs:466396
UUID:
uuid:f8839c0f-4bb1-45da-a94c-cb030ce2b74a
Local pid:
pubs:466396
Source identifiers:
466396
Deposit date:
2014-06-18

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