Journal article
Co-delivery of PLGA encapsulated invariant NKT cell agonist with antigenic protein induce strong T cell-mediated antitumor immune responses
- Abstract:
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Antitumor immunity can be enhanced by the coordinated release and delivery of antigens and immune-stimulating agents to antigen-presenting cells via biodegradable vaccine carriers. So far, encapsulation of TLR ligands and tumor-associated antigens augmented cytotoxic T cell (CTLs) responses. Here, we compared the efficacy of the invariant NKT (iNKT) cell agonist α-galactosylceramide (α-GalCer) and TLR ligands (R848 and poly I:C) as an adjuvant for the full length ovalbumin (OVA) in PLGA nanop...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 941.8KB)
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- Publisher copy:
- 10.1080/2162402X.2015.1068493
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Authors
Bibliographic Details
- Publisher:
- Taylor and Francis Publisher's website
- Journal:
- Oncoimmunology Journal website
- Volume:
- 5
- Issue:
- 1
- Pages:
- e1068493
- Publication date:
- 2015-08-12
- Acceptance date:
- 2015-06-27
- DOI:
- EISSN:
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2162-402X
- ISSN:
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2162-4011
- Source identifiers:
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598738
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:598738
- UUID:
-
uuid:f8834c73-8357-4245-b3b1-fb37bf61d2f0
- Local pid:
- pubs:598738
- Deposit date:
- 2016-06-07
Terms of use
- Copyright holder:
- Yusuf Dolen et al
- Copyright date:
- 2015
- Notes:
-
This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
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