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Computational modeling of cerebral aneurysm formation - Framework for modeling the interaction between fluid dynamics, signal transduction pathways and arterial wall mechanics

Abstract:
Many phenomenological models of cerebral aneurysm formation have been proposed. Such studies have focused on modeling the structural adaption of the arterial wall. However, further development is required to accurately represent the underlying mechanobiology during growth and remodeling processes. Here, we present a general framework for modeling the interplay of fluid dynamics, molecular signaling pathways and arterial wall mechanics. © 2009 Springer Berlin Heidelberg.

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
Journal:
IFMBE Proceedings More from this journal
Volume:
22
Pages:
1894-1898
Publication date:
2008-01-01
DOI:
ISSN:
1680-0737
Language:
English
Keywords:
Pubs id:
pubs:295959
UUID:
uuid:f84a2469-9d81-4ab4-bb61-01c9405b6afc
Local pid:
pubs:295959
Source identifiers:
295959
Deposit date:
2012-12-20

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