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Hyperpolarized 13C MRI: path to clinical translation in oncology

Abstract:

This white paper discusses prospects for advancing hyperpolarization technology to better understand cancer metabolism, identify current obstacles to HP (hyperpolarized) 13C magnetic resonance imaging's (MRI's) widespread clinical use, and provide recommendations for overcoming them. Since the publication of the first NIH white paper on hyperpolarized 13C MRI in 2011, preclinical studies involving [1-13C]pyruvate as well a number of other 13C labeled metabolic substrates have demonstrated thi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0001-6167-6926
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Role:
Author
ORCID:
0000-0002-8574-154X
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Role:
Author
ORCID:
0000-0003-3883-6287
Publisher:
Elsevier
Journal:
Neoplasia More from this journal
Volume:
21
Issue:
1
Pages:
1-16
Publication date:
2018-11-23
Acceptance date:
2018-09-27
DOI:
EISSN:
1476-5586
ISSN:
1522-8002
Pmid:
30472500
Language:
English
Pubs id:
pubs:948932
UUID:
uuid:f8477a18-c8da-4274-af7e-51142b7a03ed
Local pid:
pubs:948932
Source identifiers:
948932
Deposit date:
2019-02-01

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