Journal article icon

Journal article

Iron homeostasis and its interaction with prolyl hydroxylases.

Abstract:

The ability of iron to accept or donate electrons, coupled with the ability of oxygen to act as an electron acceptor, renders both elements essential to normal cellular biology. However, these same chemical properties allow free iron in solution to generate toxic free radicals, particularly in combination with oxygen. Thus, closely interwoven homeostatic mechanisms have evolved to regulate both iron and oxygen concentrations at the systemic and the cellular levels. Systemically, iron levels a...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1089/ars.2009.2790

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, CCMP
Journal:
Antioxidants and redox signaling
Volume:
12
Issue:
4
Pages:
445-458
Publication date:
2010-04-05
DOI:
EISSN:
1557-7716
ISSN:
1523-0864
URN:
uuid:f843b392-3e22-4c76-950d-da14f475059c
Source identifiers:
5516
Local pid:
pubs:5516

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP