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Proteomic analysis of the maternal protein restriction rat model for schizophrenia: identification of translational changes in hormonal signaling pathways and glutamate neurotransmission.

Abstract:

Previous studies have found that some first onset schizophrenia patients show signs of impaired insulin signaling. Also, epidemiological studies have shown that periods of suboptimal nutrition including protein deficiencies during pregnancy can lead to increased incidence of metabolic conditions and psychiatric disorders in the offspring. For these reasons, we have carried out a molecular profiling analysis of blood serum and brain tissues from adult offspring produced by the maternal low pro...

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Publisher copy:
10.1002/pmic.201200376

Authors


Stelzhammer, V More by this author
Harris, LW More by this author
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Journal:
Proteomics
Volume:
12
Issue:
23-24
Pages:
3580-3589
Publication date:
2012-12-05
DOI:
EISSN:
1615-9861
ISSN:
1615-9853
URN:
uuid:f834159f-1664-4613-908f-4a20b2301501
Source identifiers:
487342
Local pid:
pubs:487342

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