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In vitro activity of ferroquine (SSR 97193) against Plasmodium falciparum isolates from the Thai-Burmese border.

Abstract:

BACKGROUND: On the borders of Thailand, Plasmodium falciparum has become resistant to nearly all available drugs, and there is an urgent need to find new antimalarial drugs or drug combinations. Ferroquine (SSR97193) is a new 4-aminoquinoline antimalarial active against chloroquine resistant and sensitive P. falciparum strains in vivo and in vitro. This antimalarial organic iron complex (a ferrocenyl group has been associated with chloroquine) is meant to use the affinity of Plasmodium for i...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1475-2875-6-81

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Publisher:
BioMed Central
Journal:
Malaria Journal More from this journal
Volume:
6
Issue:
1
Article number:
81
Publication date:
2007-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
Language:
English
Keywords:
Pubs id:
pubs:9711
UUID:
uuid:f811ebca-3c2e-4e68-83e5-009da8d97b10
Local pid:
pubs:9711
Source identifiers:
9711
Deposit date:
2012-12-19

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