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New magnetic nano-absorbent for the determination of n-octanol/water partition coefficients

Abstract:

A novel and generic miniaturization methodology for the determination of partition coefficient values of organic compounds in n-octanol/water by using magnetic nanoparticles is, for the first time, described. We have successfully designed, synthesised and characterised new colloidal stable porous silica-encapsulated magnetic nanoparticles of controlled dimensions. These nanoparticles absorbing a tiny amount of n-octanol in their porous silica over-layer are homogeneously dispersed into a bulk...

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Publisher copy:
10.1016/j.jpba.2004.12.029
Journal:
Journal of Pharmaceutical and Biomedical Analysis More from this journal
Volume:
38
Issue:
2
Pages:
197-203
Publication date:
2005-06-15
DOI:
ISSN:
0731-7085
Language:
English
Keywords:
Pubs id:
pubs:180221
UUID:
uuid:f807555a-8b6e-4c12-96db-ce9ffd23bef0
Local pid:
pubs:180221
Source identifiers:
180221
Deposit date:
2012-12-19

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