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Journal article

Multimodal functional cardiac MRI in creatine kinase-deficient mice reveals subtle abnormalities in myocardial perfusion and mechanics.

Abstract:

A decrease in the supply of ATP from the creatine kinase (CK) system is thought to contribute to the evolution of heart failure. However, previous studies on mice with a combined knockout of the mitochondrial and cytosolic CK (CK(-/-)) have not revealed overt left ventricular dysfunction. The aim of this study was to employ novel MRI techniques to measure maximal myocardial velocity (V(max)) and myocardial perfusion and thus determine whether abnormalities in the myocardial phenotype existed ...

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Publication status:
Published

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Publisher copy:
10.1152/ajpheart.01038.2005

Authors


Journal:
American journal of physiology. Heart and circulatory physiology More from this journal
Volume:
290
Issue:
6
Pages:
H2516-H2521
Publication date:
2006-06-01
DOI:
EISSN:
1522-1539
ISSN:
0363-6135
Language:
English
Keywords:
Pubs id:
pubs:124848
UUID:
uuid:f8074354-2065-42e9-bb9c-bf7ffd1ebb97
Local pid:
pubs:124848
Source identifiers:
124848
Deposit date:
2012-12-19

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