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Journal article

Microvesicles and exosomes: opportunities for cell-derived membrane vesicles in drug delivery.

Abstract:

Cell-derived membrane vesicles (CMVs) are endogenous carriers transporting proteins and nucleic acids between cells. They appear to play an important role in many disease processes, most notably inflammation and cancer, where their efficient functional delivery of biological cargo seems to contribute to the disease progress. CMVs encompass a variety of submicron vesicular structures that include exosomes and shedding vesicles. The lipids, proteins, mRNA and microRNA (miRNA) delivered by these...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Journal of controlled release : official journal of the Controlled Release Society More from this journal
Volume:
161
Issue:
2
Pages:
635-644
Publication date:
2012-07-01
DOI:
EISSN:
1873-4995
ISSN:
0168-3659
Language:
English
Keywords:
Pubs id:
pubs:222485
UUID:
uuid:f7fd73b3-bbd3-48ea-bd7e-96877a532401
Local pid:
pubs:222485
Source identifiers:
222485
Deposit date:
2012-12-19

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