- The CancerGrid approach to software support for clinical trials is based on two principles: careful curation of semantic metadata about clinical observations, to enable subsequent data integration, and model-driven generation of trial-specific software artefacts from a trial protocol, to streamline the software development process. This paper explains the approach, presents four varied case studies, and discusses the lessons learned. © 2013 Elsevier B.V. All rights reserved.
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The CancerGrid experience: Metadata-based model-driven engineering for clinical trials
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