- Abstract:
-
Several genetic loci appear to be involved in susceptibility to autoimmune disease. Some loci are disease specific, whereas others appear to exert a general effect on the autoimmune disease process. Despite a large number of studies of many different diseases, consistent associations with multiple autoimmune disorders have been restricted to three gene regions: the human leukocyte antigen (HLA) class II region on chromosome 6p21, the gene encoding cytotoxic T lymphocyte-associated 4 (CTLA-4) ...
Expand abstract - Publisher copy:
- 10.1017/S1462399405009981
-
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- Journal:
- Expert reviews in molecular medicine
- Volume:
- 7
- Issue:
- 23
- Pages:
- 1-15
- Publication date:
- 2005-10-05
- DOI:
- EISSN:
-
1462-3994
- ISSN:
-
1462-3994
- URN:
-
uuid:f7eee9e9-727f-4114-b776-1282b58c5171
- Source identifiers:
-
175994
- Local pid:
- pubs:175994
- Copyright date:
- 2005
Journal article
HLA , CTLA-4 and PTPN22 : the shared genetic master-key to autoimmunity?
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