Dynamic release and clearance of circulating microparticles during cardiac stress.
RATIONALE: Microparticles are cell-derived membrane vesicles, relevant to a range of biological responses and known to be elevated in cardiovascular disease. OBJECTIVE: To investigate microparticle release during cardiac stress and how this response differs in those with vascular disease. METHODS AND RESULTS: We measured a comprehensive panel of circulating cell-derived microparticles by a standardized flow cytometric protocol in 119 patients referred for stress echocardiography. Procoagulant...Expand abstract
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