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Brain tissue oxygen amperometry in behaving rats demonstrates functional dissociation of dorsal and ventral hippocampus during spatial processing and anxiety.

Abstract:

Traditionally, the function of the hippocampus (HPC) has been viewed in unitary terms, but there is growing evidence that the HPC is functionally differentiated along its septotemporal axis. Lesion studies in rodents and functional brain imaging in humans suggest a preferential role for the septal HPC in spatial learning and a preferential role for the temporal HPC in anxiety. To better enable cross-species comparison, we present an in vivo amperometric technique that measures changes in brai...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
The European journal of neuroscience
Volume:
33
Issue:
2
Pages:
322-337
Publication date:
2011-01-05
DOI:
EISSN:
1460-9568
ISSN:
0953-816X
URN:
uuid:f7c4f2a5-cf8d-46cd-8776-593f374f7a73
Source identifiers:
97289
Local pid:
pubs:97289

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