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Age-structured non-pharmaceutical interventions for optimal control of COVID-19 epidemic

Abstract:

In an epidemic, individuals can widely differ in the way they spread the infection depending on their age or on the number of days they have been infected for. In the absence of pharmaceutical interventions such as a vaccine or treatment, non-pharmaceutical interventions (e.g. physical or social distancing) are essential to mitigate the pandemic. We develop an original approach to identify the optimal age-stratified control strategy to implement as a function of the time since the onset of th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pcbi.1008776

Authors


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Role:
Author
ORCID:
0000-0003-2450-3350
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Role:
Author
ORCID:
0000-0002-0779-9543
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-5187-6390
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Role:
Author
ORCID:
0000-0002-4499-0435
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Role:
Author
ORCID:
0000-0003-1684-5190
Publisher:
Public Library of Science
Journal:
PLoS Computational Biology More from this journal
Volume:
17
Issue:
3
Article number:
e1008776
Publication date:
2021-03-04
Acceptance date:
2021-02-07
DOI:
EISSN:
1553-7358
ISSN:
1553-734X
Pmid:
33661890

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