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Regionally localized thinning of the cerebral cortex in schizophrenia.

Abstract:

BACKGROUND: Schizophrenia is characterized by small reductions in cortical gray matter volume, particularly in the temporal and prefrontal cortices. The question of whether cortical thickness is reduced in schizophrenia has not been addressed using magnetic resonance imaging (MRI) techniques. Our objectives were to test the hypothesis that cortical thinning in patients with schizophrenia (relative to control subjects) is greater in temporal and prefrontal regions of interest (ROIs) than in c...

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Publisher copy:
10.1001/archpsyc.60.9.878

Authors


Journal:
Archives of general psychiatry More from this journal
Volume:
60
Issue:
9
Pages:
878-888
Publication date:
2003-09-01
DOI:
EISSN:
1538-3636
ISSN:
0003-990X
Language:
English
Keywords:
Pubs id:
pubs:403473
UUID:
uuid:f78d516a-498e-4a72-9109-0d1d37dfea56
Local pid:
pubs:403473
Source identifiers:
403473
Deposit date:
2013-11-16

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