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Cargo-dependent cytotoxicity and delivery efficacy of cell-penetrating peptides: a comparative study.

Abstract:

The use of CPPs (cell-penetrating peptides) as delivery vectors for bioactive molecules has been an emerging field since 1994 when the first CPP, penetratin, was discovered. Since then, several CPPs, including the widely used Tat (transactivator of transcription) peptide, have been developed and utilized to translocate a wide range of compounds across the plasma membrane of cells both in vivo and in vitro. Although the field has emerged as a possible future candidate for drug delivery, little...

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Publisher copy:
10.1042/bj20070507
Journal:
Biochemical journal More from this journal
Volume:
407
Issue:
2
Pages:
285-292
Publication date:
2007-10-01
DOI:
EISSN:
1470-8728
ISSN:
0264-6021
Language:
English
Keywords:
Pubs id:
pubs:264708
UUID:
uuid:f787dfc2-1dda-46e6-b215-e049d41deacc
Local pid:
pubs:264708
Source identifiers:
264708
Deposit date:
2013-11-16

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