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Sperm Factors and Oocyte Activation: Current Controversies and Considerations.

Abstract:

The beginning of embryogenesis is preceded by a sequence of events mediated by the release of intracellular calcium in the ooplasm, a multifaceted process known as oocyte activation. It is now well established that a sperm protein factor introduced into the oocyte at the time of gamete fusion is responsible for initiating the cascade of signaling events involved. Several sperm proteins have been hypothesized as the sperm oocyte-activating factor (SOAF) over the years, with phospholipase C zet...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1095/biolreprod.115.130609

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
More from this funder
Name:
European Union
Funding agency for:
Yeste, M
Grant:
Marie Curie IEF Fellowship
More from this funder
Name:
Universiti Brunei Darussalam
Funding agency for:
Amdani, S
Grant:
Chancellor’s Scholarship
Publisher:
Society for the Study of Reproduction
Journal:
Biology of reproduction More from this journal
Volume:
93
Issue:
2
Pages:
50
Publication date:
2015-07-08
DOI:
EISSN:
1529-7268
ISSN:
0006-3363
Language:
English
Keywords:
Pubs id:
pubs:531629
UUID:
uuid:f77232b0-280e-4f12-9501-2ed1c85e3d30
Local pid:
pubs:531629
Source identifiers:
531629
Deposit date:
2015-12-26

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