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Population dynamics of HIV-2 in rural West Africa: comparison with HIV-1 and ongoing transmission at the heart of the epidemic.

Abstract:

OBJECTIVES: To compare the population dynamics of HIV-2 and HIV-1, and to characterize ongoing HIV-2 transmission in rural Guinea-Bissau. DESIGN: Phylogenetic and phylodynamic analyses using HIV-2 gag and env, and HIV-1 env sequences, combined with epidemiological data from a community cohort. METHODS: Samples were obtained from surveys in 1989-1991, 1996-1997, 2003 and 2006-2007. Phylogenies were reconstructed using sequences from 103 HIV-2-infected and 56 HIV-1-infected patients using Bayes...

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Publication status:
Published

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Journal:
AIDS (London, England) More from this journal
Volume:
27
Issue:
1
Pages:
125-134
Publication date:
2013-01-01
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
Language:
English
Keywords:
Pubs id:
pubs:353926
UUID:
uuid:f75ee640-0280-4c6c-89f2-38fdcf1a65fa
Local pid:
pubs:353926
Source identifiers:
353926
Deposit date:
2013-11-16

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