Journal article

Ready display of antigenic peptides in a protein 'mimogen'.

Abstract:: Given the dependence of much modern biology upon the use of antibodies as tools and reagents, their variability and the often associated lack-of-detail about function and identity creates experimental errors. Here we describe the proof-of-principle for a potentially general, versatile method for the display of antigens in a soluble yet standard format on a lateral protein scaffold that mimics normal epitopes in a protein antigen (a 'mimogen') and confirm their utility in phosphorylation-dependent recognition by specific antibodies.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Vallée, M., Schombs, M., Balaban, Z., Colyer, J., & Davis, B. (2016). Ready display of antigenic peptides in a protein 'mimogen'. Chemical Communications, 52(14), 3014–3017.

MLA Style

Vallée, M, et al. “Ready Display of Antigenic Peptides in a Protein 'Mimogen'.” Chemical Communications, vol. 52, no. 14, 2016, pp. 3014–17.

Chicago Style

Vallée, M, M Schombs, Z Balaban, J Colyer, and B Davis. 2016. “Ready Display of Antigenic Peptides in a Protein 'Mimogen'.” Chemical Communications 52 (14): 3014–17.
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Publisher copy:: 10.1039/c5cc08892e

Authors

+ Vallée, M More by this author

Role:: Author

+ Schombs, M More by this author

Role:: Author

+ Balaban, Z More by this author

Role:: Author

+ Colyer, J More by this author

Role:: Author

+ Davis, B More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

+ Engineering and Physical Sciences Research Council More from this funder

Grant:: EP/I500200/1; EP/K503769/1

Publisher:: Royal Society of Chemistry
Journal:: Chemical Communications More from this journal
Volume:: 52
Issue:: 14
Pages:: 3014-3017
Publication date:: 2016-01-01
Acceptance date:: 2016-01-06
DOI:: 10.1039/c5cc08892e
EISSN:: 1364-548X
ISSN:: 1359-7345

Language:: English
Pubs id:: pubs:597977
UUID:: uuid:f74dc276-e38f-4b7e-b721-3431852ce428
Local pid:: pubs:597977
Source identifiers:: 597977
Deposit date:: 2016-02-23
ARK identifier:: ark:/29072/ora_f74dc276e38f4b7eb7213431852ce428

Terms of use

Copyright holder:: Vallée et al
Copyright date:: 2016
Notes:: The full text of this article is not currently available in ORA.

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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