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Thyrotrophin-releasing hormone, vasoactive intestinal peptide, prolactin-releasing peptide and dopamine regulation of prolactin secretion by different lactotroph morphological subtypes in the rat.

Abstract:

In the male rat anterior pituitary, three morphological subtypes of cells secreting primarily prolactin (PRL) (lactotrophs) have been described. Type I contain predominantly large irregularly shaped granules, whereas type II and type III lactotrophs contain smaller spherical granules. We have previously shown that oestradiol and testosterone exert a rapid stimulatory effect selectively on type II lactotrophs but it is not known how the lactotroph subtypes respond to peptide secretagogues. We ...

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Published

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Journal of neuroendocrinology More from this journal
Volume:
19
Issue:
8
Pages:
605-613
Publication date:
2007-08-01
DOI:
EISSN:
1365-2826
ISSN:
0953-8194
Language:
English
Keywords:
Pubs id:
pubs:114341
UUID:
uuid:f74cf93f-0f0f-4432-9c35-6b0a0a38075f
Local pid:
pubs:114341
Source identifiers:
114341
Deposit date:
2012-12-19

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