Building bridges to the cortex.

Journal article

Innervation of the neocortex by the thalamus is dependent on the precise coordination of spatial and temporal guidance cues. In this issue of Cell, work by López-Bendito et al.(2006) reveals that tangentially migrating cells within the ventral telencephalon are essential for axonal navigation between the thalamus and the neocortex, a process apparently mediated by Neuregulin-1/ErbB4 short- and long-range signaling.

Authors: Hanashima, C; Molnár, Z; Fishell, G

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Cell Press
• Journal: Cell
• Volume: 125
• Issue: 1
• Pages: 24-27
• Publication date: 2006-04-01
• DOI: 10.1016/j.cell.2006.03.021
• EISSN: 1097-4172
• ISSN: 0092-8674
• Language: English
• Keywords: Animals; Signal Transduction; Neuregulin-1; Cerebral Cortex; Receptor, Epidermal Growth Factor; Thalamus; Cell Movement; Axons