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The systemic response to CNS injury.

Abstract:

Inflammation within the brain or spinal cord has the capacity to damage neurons and is known to contribute to long-term disability in a spectrum of central nervous system (CNS) pathologies. However, there is a more profound increase in the recruitment of potentially damaging populations of leukocytes to the spinal cord than to the brain after equivalent injuries. Increased levels of inflammatory cytokines and chemokines in the spinal cord underpin this dissimilarity after injury, which also a...

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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Role:
Author
Journal:
Experimental neurology
Volume:
258
Pages:
105-111
Publication date:
2014-08-05
DOI:
EISSN:
1090-2430
ISSN:
0014-4886
URN:
uuid:f72dc36f-cc41-44ae-ab45-76b3fe1a6c60
Source identifiers:
478339
Local pid:
pubs:478339

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