- Abstract:
-
Dopamine (DA) neurotransmission in the nucleus accumbens (NAc) is critically involved in normal as well as maladaptive motivated behaviors including drug addiction. Whether the striatal neuromodulator nitric oxide (NO) influences DA release in NAc is unknown. We investigated whether exogenous NO modulates DA transmission in NAc core and how this interaction varies depending on the frequency of presynaptic activation. We detected DA with cyclic voltammetry at carbon-fiber microelectrodes in mo...
Expand abstract - Publisher copy:
- 10.1038/npp.2011.62
-
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- Journal:
- Neuropsychopharmacology
- Volume:
- 36
- Issue:
- 9
- Pages:
- 1811-1822
- Publication date:
- 2011-08-05
- DOI:
- EISSN:
-
1740-634X
- ISSN:
-
0893-133X
- URN:
-
uuid:f72b9173-983b-445c-8718-ba3d5066ffbf
- Source identifiers:
-
167724
- Local pid:
- pubs:167724
- Language:
- English
- Keywords:
- Copyright date:
- 2011
Journal article
Nitric oxide donors enhance the frequency dependence of dopamine release in nucleus accumbens
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