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Utility of aquaporin-4 antibody assay in patients with neuromyelitis optica spectrum disorders.

Abstract:

OBJECTIVE: Our aim was to evaluate the utility of aquaporin-4 antibodies (AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD). METHODS: The clinical and radiological characteristics of 78 patients with NMOSD and 22 with multiple sclerosis (MS), who were tested for AQP4-Ab by a cell-based assay, were assessed. RESULTS: The mean time interval between symptom onset and development of optic neuritis and myelitis was 39.9 months in neuromyelitis optica (NMO). About 40% of pat...

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Publication status:
Published

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Publisher copy:
10.1177/1352458512472748

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
Multiple sclerosis (Houndmills, Basingstoke, England)
Volume:
19
Issue:
8
Pages:
1060-1067
Publication date:
2013-07-05
DOI:
EISSN:
1477-0970
ISSN:
1352-4585
URN:
uuid:f7266076-2fcf-4b7a-b243-f425cb71b112
Source identifiers:
443689
Local pid:
pubs:443689

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