Journal article icon

Journal article

Sleep and circadian rhythm disturbances: multiple genes and multiple phenotypes

Abstract:

Sleep is regulated by two broad mechanisms: the circadian system, which generates 24-h rhythms of sleep propensity and a wake-dependent homeostatic sleep process whereby sleep pressure increases during wake and dissipates during sleep. These, in turn, regulate multiple brain structures and neurotransmitter systems. In view of the complexity of sleep it is not surprising that there is considerable variation between individuals in both sleep timing and propensity. Furthermore, marked abnormalit...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1016/j.gde.2009.03.007

Authors


More by this author
Institution:
University of Oxford
Research group:
Circadian and Visual Neuroscience
Department:
Medical Sciences Division - Ophthalmology
Role:
Author
More by this author
Institution:
University of Oxford
Research group:
Circadian and Visual Neuroscience
Department:
Medical Sciences Division - Ophthalmology
Role:
Author
More by this author
Institution:
University of Oxford
Research group:
Circadian and Visual Neuroscience
Department:
Medical Sciences Division - Ophthalmology
Role:
Author
More by this author
Institution:
University of Oxford
Research group:
Circadian and Visual Neuroscience
Department:
Medical Sciences Division - Ophthalmology
Role:
Author
NIHR Biomedical Research Centre, Oxford, UK More from this funder
Wellcome Trust More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Current Opinion in Genetics & Development Journal website
Volume:
19
Issue:
3
Pages:
237-246
Publication date:
2009-06-05
DOI:
ISSN:
0959-437X
URN:
uuid:f725c0bd-8f8d-4608-bb4d-6c153775b38c
Local pid:
ora:4612
Language:
English
Keywords:
Subjects:

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP