- Abstract:
-
UNLABELLED: Current therapy of chronic hepatitis C is based on the combination of pegylated interferon-alpha and ribavirin. In spite of 50% sustained virological response, therapy is still limited by unsatisfying success rates with genotype 1 infections and adverse side effects. One attempt to increase success rates is triple combination therapy of interferon and ribavirin with amantadine, a drug assumed to interfere with HCV p7 ion channel function. However, results from clinical trials ind...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/hep.21686
-
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- Journal:
- Hepatology (Baltimore, Md.)
- Volume:
- 46
- Issue:
- 2
- Pages:
- 330-338
- Publication date:
- 2007-08-05
- DOI:
- EISSN:
-
1527-3350
- ISSN:
-
0270-9139
- URN:
-
uuid:f721e3f8-b5da-4ca8-9d54-d55638fe336d
- Source identifiers:
-
100157
- Local pid:
- pubs:100157
- Copyright date:
- 2007
Journal article
Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus.
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