- Abstract:
-
BACKGROUND: Chloroquine resistance in Plasmodium falciparum malaria has been associated with pfcrt 76T (chloroquine resistance transporter gene) and pfmdr1 86Y (multidrug resistance gene 1) alleles. Pfcrt 76T enables transport of protonated chloroquine out of the parasites digestive vacuole resulting in a loss of hydrogen ions (H(+)). V type H(+) pyrophosphatase (PfVP2) is thought to pump H(+) into the digestive vacuole. This study aimed to describe the geographic distribution of single nucle...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.meegid.2014.03.004
-
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- Journal:
- Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
- Volume:
- 24
- Pages:
- 111-115
- Chapter number:
- C
- Publication date:
- 2014-06-05
- DOI:
- EISSN:
-
1567-7257
- ISSN:
-
1567-1348
- URN:
-
uuid:f71f89e7-7146-44e8-a51c-13dcd9d7b89b
- Source identifiers:
-
458785
- Local pid:
- pubs:458785
- Language:
- English
- Keywords:
- Copyright date:
- 2014
- Notes:
-
publisher: Elsevier
articletitle: Single nucleotide polymorphisms in Plasmodium falciparum V type H+ pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms
journaltitle: Infection, Genetics and Evolution
articlelink: http://dx.doi.org/10.1016/j.meegid.2014.03.004
content_type: article
copyright: Copyright © 2014 Elsevier B.V. All rights reserved.
Journal article
Single nucleotide polymorphisms in Plasmodium falciparum V type H(+) pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms.
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