Matrix-Induced Autologous Chondrocyte Implantation

Journal article

Matrix-induced autologous chondrocyte implantation is a third-generation autologous chondrocyte implantation technique that can be used for treating chondral and osteochondral lesions. Harvested chondrocytes are expanded in number and seeded onto a type I/III collagen membrane. The matrix-induced autologous chondrocyte implantation graft is secured within the debrided defect with fibrin sealant, which produces a stable reconstruction. Most clinical experience relates to its use in the knee joint, where a number of series report good clinical outcome up to 5 years postsurgery. © 2006 Elsevier Inc. All rights reserved.

Authors: Gibson, A; McDonnell, S; Price, A

• Journal: Operative Techniques in Orthopaedics
• Volume: 16
• Issue: 4
• Pages: 262-265
• Publication date: 2006-10-01
• DOI: 10.1053/j.oto.2006.09.004
• ISSN: 1048-6666
• Language: English
• Keywords: surgical technique; outcome; osteochondral defect; chondrocyte; matrix-induced autologous chondrocyte implantation (MACI)