- Abstract:
-
Cloning procedures aided by homology searches of EST databases have accelerated the pace of discovery of new genes, but EST database searching remains an involved and onerous task. More than 1.6 million human EST sequences have been deposited in public databases, making it difficult to identify ESTs that represent new genes. Compounding the problems of scale are difficulties in detection associated with a high sequencing error rate and low sequence similarity between distant homologues. We ha...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/76069
-
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- Journal:
- Nature genetics
- Volume:
- 25
- Issue:
- 2
- Pages:
- 201-204
- Publication date:
- 2000-06-05
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- URN:
-
uuid:f6f17c29-8976-4ebd-b63c-57584d4260be
- Source identifiers:
-
54223
- Local pid:
- pubs:54223
- Language:
- English
- Keywords:
- Copyright date:
- 2000
Journal article
More than 1,000 putative new human signalling proteins revealed by EST data mining.
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