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tidal ventilation model for oxygenation in respiratory failure

Abstract:
We develop tidal-ventilation pulmonary gas-exchange equations that allow pulmonary shunt to have different values during expiration and inspiration, in accordance with lung collapse and recruitment during lung dysfunction [Am. J. Respir. Crit. Care Med. 158 (1998) 1636]. Their solutions are tested against published animal data from intravascular oxygen tension and saturation sensors. These equations provide one explanation for (i) observed physiological phenomena, such as within-breath fluctuations in arterial oxygen saturation and blood-gas tension; and (ii) conventional (time averaged) blood-gas sample ox

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Journal:
RESPIRATORY PHYSIOLOGY and NEUROBIOLOGY     More from this journal
Volume:
136
Issue:
1
Pages:
77-88
Publication date:
2003-01-01


UUID:
uuid:f6f0b7f6-5330-4da5-b569-6a53352a855c
Local pid:
cs:4326
Deposit date:
2015-03-31
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