Journal article
Complex ancient genetic structure and cultural transitions in southern African populations
- Abstract:
- The characterization of the structure of southern Africa populations has been the subject of numerous genetic, medical, linguistic, archaeological and anthropological investigations. Current diversity in the subcontinent is the result of complex events of genetic admixture and cultural contact between early inhabitants and migrants that arrived in the region over the last 2,000 years. Here we analyze 1,856 individuals from 91 populations, comprising novel and published genotype data, to characterize the genetic ancestry profiles of 631 individuals from 51 southern African populations. Combining both local ancestry and allele frequency based analyses we identify a tripartite, ancient, Khoesan-related genetic structure. This structure correlates neither with linguistic affiliation nor subsistence strategy, but with geography, revealing the importance of isolation by distance dynamics in the area. Fine-mapping of these components in southern African populations reveals that admixture and cultural reversion involving several Khoesan groups and highlights that Bantu speakers and Coloured individuals have different mixtures of these ancient ancestries.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.3MB, Terms of use)
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- Publisher copy:
- 10.1534/genetics.116.189209
Authors
+ Portuguese Foundation for Science and Technology
More from this funder
- Funding agency for:
- dos Santos, M
- Grant:
- SFRH/BD/90648/2012
- Publisher:
- Genetics Society of America
- Journal:
- Genetics More from this journal
- Volume:
- 205
- Issue:
- 1
- Pages:
- 303-316
- Publication date:
- 2017-01-03
- Acceptance date:
- 2016-10-14
- DOI:
- EISSN:
-
1943-2631
- ISSN:
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0016-6766
- Pubs id:
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pubs:652471
- UUID:
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uuid:f6ec9a29-c39a-49f3-80f0-8e70808053eb
- Local pid:
-
pubs:652471
- Source identifiers:
-
652471
- Deposit date:
-
2016-10-14
Terms of use
- Copyright holder:
- Montinaro et al
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 Montinaro et al. Available freely online through the author-supported open access option. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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